Long story short – it’s possible.
I was concerned that after having PLA ooze through the threads that I would be forced to use my backup PTFE barrier. However, I’ve been pleasantly surprised to discover that I can print just fine with my reassembled unclogged extruder. I’ve been able to print several things without so much as a hiccup.
So be delicate with your PTFE even after plastic has oozed into the threads – you may just be able to use it if you can clear out the plastic from the threads.